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1. Barber MF, Lee EM, Griffin H, Elde NC: Rapid Evolution of Primate Type 2 Immune Response Factors Linked to Asthma Susceptibility. Genome Biol Evol; 2017 Jun 01;9(6):1757-1765

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Microbial infections can also trigger excessive inflammation that contributes to diverse autoimmune disorders including asthma, lupus, diabetes, and arthritis.

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  • [Copyright] © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.
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  • (PMID = 28854632.001).
  • [ISSN] 1759-6653
  • [Journal-full-title] Genome biology and evolution
  • [ISO-abbreviation] Genome Biol Evol
  • [Language] eng
  • [Grant] United States / NIGMS NIH HHS / GM / R01 GM114514
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; asthma genetics / eosinophil granule protein / human variation / interleukin 13 / primate evolution
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2. Wu TC, Lu Q, Huang ZY, Liang XH: Efficacy of emergency laparoscopic appendectomy in treating complicated appendicitis for elderly patients. Saudi Med J; 2017 Nov;38(11):1108-1112

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  •  Methods: We conducted a retrospective study of 115 elderly patients with CA who underwent surgical therapy in the Affiliated Huizhou Hospital of Sun Yat-Sun University, Huizhou, Guangdong Province, China between September 2014 and August 2016.
  •  Results: The operative time in the LA group was longer than the OA group (LA: 70.5±16.0 min versus [vs.] OA: 59.3±12.0 min, p greater than 0.001).
  • The LA group had lower chances of incision infections (LA: 8.9% vs OA: 28.8 %, p=0.007) and shorter hospital stay (LA: 6.1± 2.5 days vs.
  • Return to soft diet (LA: 1.4 ± 0.8 days vs OA: 3.0 ± 1.6 days, p greater than 0.001) and time to out of bed (LA: 1.3±0.5 days vs OA: 2.5±0.9 days, p greater than 0.001) was faster in the LA group.

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  • (PMID = 29114698.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Saudi Arabia
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3. Frazzoli C, Mazzanti F, Achu MB, Pouokam GB, Fokou E: Elements of kitchen toxicology to exploit the value of traditional (African) recipes: The case of <i>Egusi Okra</i> meal in the diet of HIV+/AIDS subjects. Toxicol Rep; 2017;4:474-483
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The <i>Egusi Okra</i> soup is discussed in the context of a diet that is asked to mitigate complications (weight loss, opportunistic infections) and support antiretroviral therapy in African countries with high HIV/AIDS prevalence.

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  • (PMID = 28959677.001).
  • [ISSN] 2214-7500
  • [Journal-full-title] Toxicology reports
  • [ISO-abbreviation] Toxicol Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  • [Keywords] NOTNLM ; Aluminium (PubChem CID: 5359268) / Arsenic (PubChem CID: 5359596) / Benzo(a)pyrene (PubChem CID: 2336) / Bis(2-ethylhexyl) phthalate (PubChem CID: 8343) / Bisphenol A (PubChem CID: 6623) / Clinical toxicology / Deoxynivalenol (PubChem CID: 16212213) / Dysmetabolic diseases / Food safety / Hexachlorobenzene (PubChem CID: 8370) / Immune system / Malnutrition / Nutrition security / Perfluoro-octanoic acid (PubChem CID: 9554) / Selenium (PubChem CID: 6326970) / Traditional diet / Weight loss / Zinc (PubChem CID: 23994)
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4. Krivan G, Chernyshova L, Kostyuchenko L, Lange A, Nyul Z, Derfalvi B, Musial J, Bellon A, Kappler M, Sadoun A, Bernatowska E: A Multicentre Study on the Efficacy, Safety and Pharmacokinetics of IqYmune®, a Highly Purified 10% Liquid Intravenous Immunoglobulin, in Patients with Primary Immune Deficiency. J Clin Immunol; 2017 Aug;37(6):539-547

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A single case of serious bacterial infection was observed, leading to an annualized rate of serious bacterial infections/patient (primary endpoint) of 0.017 (98% CI: 0.000, 0.115).
  • Overall, 228 infections were reported, most frequently bronchitis, chronic sinusitis, nasopharyngitis and upper respiratory tract infection.
  • The mean annualized rate of infections was 3.79/patient.
  • A lower risk of infections was associated with an IgG trough level > 8 g/L (p = 0.01).
  • The mean annualized durations of absence from work or school and of hospitalization due to infections were 1.01 and 0.89 days/patient, respectively.

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  • (PMID = 28711959.001).
  • [ISSN] 1573-2592
  • [Journal-full-title] Journal of clinical immunology
  • [ISO-abbreviation] J. Clin. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Keywords] NOTNLM ; Clinical trials / IVIg / Immunoglobulins
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5. Wilburn L, Yodmeeklin A, Kochjan P, Saikruang W, Kumthip K, Khamrin P, Maneekarn N: Molecular detection and characterization of picobirnaviruses in piglets with diarrhea in Thailand. Arch Virol; 2017 Apr;162(4):1061-1066
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PBV infects a wide range of hosts and causes opportunistic infections, but its role in diarrheal disease remains unclear.
  • PBV was detected in 86 of 265 (32.5%) diarrheic piglets and in 26 of 115 (22.6%) non-diarrheic piglets.
  • [MeSH-major] Diarrhea / veterinary. Picobirnavirus / genetics. RNA Virus Infections / veterinary. Swine Diseases / virology

  • MedlinePlus Health Information. consumer health - Diarrhea.
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  • (PMID = 28032197.001).
  • [ISSN] 1432-8798
  • [Journal-full-title] Archives of virology
  • [ISO-abbreviation] Arch. Virol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Austria
  • [Keywords] NOTNLM ; Diarrhea / Picobirnavirus / Thailand
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6. Epting CL, Emmer BT, Du NY, Taylor JM, Makanji MY, Olson CL, Engman DM: Cell Cycle Inhibition To Treat Sleeping Sickness. MBio; 2017 Sep 19;8(5)

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Our results demonstrate that RNR inhibition is highly effective in suppressing parasite growth both <i>in vitro</i> and <i>in vivo</i> These results support drug discovery efforts targeting the cell cycle, not only for African trypanosomiasis but possibly also for other infections by eukaryotic pathogens.
  • <b>IMPORTANCE</b> The development of drugs to treat infections with eukaryotic pathogens is challenging because many key virulence factors have closely related homologues in humans.

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  • [Copyright] Copyright © 2017 Epting et al.
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  • (PMID = 28928213.001).
  • [ISSN] 2150-7511
  • [Journal-full-title] mBio
  • [ISO-abbreviation] MBio
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / F30 HL094026; United States / NHLBI NIH HHS / HL / R01 HL080692; United States / NCRR NIH HHS / RR / UL1 RR025741
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; African sleeping sickness / Trypanosoma brucei / hydroxyurea / ribonucleotide reductase
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7. Choi JY, Sung YB, Kim JH: Comparative Study of Bipolar Hemiarthroplasty for Femur Neck Fractures Treated with Cemented versus Cementless Stem. Hip Pelvis; 2016 Dec;28(4):208-216

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Among the 180 patients, 115 were treated with cemented stems and 65 patients with cementless stems.
  • Selective use of cemented stem in bipolar hemiarthroplasty may be a desirable treatment method for patients with poor bone quality and higher risk of infections.

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  • (PMID = 28097110.001).
  • [ISSN] 2287-3260
  • [Journal-full-title] Hip & pelvis
  • [ISO-abbreviation] Hip Pelvis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Keywords] NOTNLM ; Bipolar hemiarthroplasty / Cemented stem / Cementless stem / Femoral neck fractures
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8. Tracy KE, Baumgarth N: &lt;i&gt;Borrelia burgdorferi&lt;/i&gt; Manipulates Innate and Adaptive Immunity to Establish Persistence in Rodent Reservoir Hosts. Front Immunol; 2017;8:116

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • <i>Borrelia burgdorferi</i> sensu lato species complex is capable of establishing persistent infections in a wide variety of species, particularly rodents.

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  • (PMID = 28265270.001).
  • [ISSN] 1664-3224
  • [Journal-full-title] Frontiers in immunology
  • [ISO-abbreviation] Front Immunol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Keywords] NOTNLM ; complement inhibition / germinal center / immune evasion / immune exhaustion / lyme disease / persistent infection
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9. Kiattibutr K, Roobsoong W, Sriwichai P, Saeseu T, Rachaphaew N, Suansomjit C, Buates S, Obadia T, Mueller I, Cui L, Nguitragool W, Sattabongkot J: Infectivity of symptomatic and asymptomatic Plasmodium vivax infections to a Southeast Asian vector, Anopheles dirus. Int J Parasitol; 2017 Feb;47(2-3):163-170

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Infectivity of symptomatic and asymptomatic Plasmodium vivax infections to a Southeast Asian vector, Anopheles dirus.
  • Because the majority of Plasmodium infections in endemic areas are low density and asymptomatic, it is important to evaluate how well these infections transmit.
  • Using membrane feeding apparatus, Anopheles dirus were fed with blood samples from 94 individuals who had natural P. vivax infections with parasitemias spanning four orders of magnitude.

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  • [Copyright] Copyright © 2016. Published by Elsevier Ltd.
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  • (PMID = 28043858.001).
  • [ISSN] 1879-0135
  • [Journal-full-title] International journal for parasitology
  • [ISO-abbreviation] Int. J. Parasitol.
  • [Language] eng
  • [Grant] United Kingdom / Wellcome Trust / / ; United States / NIAID NIH HHS / AI / U19 AI089672
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Anopheles dirus / Infectivity / Malaria / Membrane feeding assay / Plasmodium vivax / Transmission
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10. Tverdek FP, Heo ST, Aitken SL, Granwehr B, Kontoyiannis DP: Real-Life Assessment of the Safety and Effectiveness of the New Tablet and Intravenous Formulations of Posaconazole in the Prophylaxis of Invasive Fungal Infections via Analysis of 343 Courses. Antimicrob Agents Chemother; 2017 Aug;61(8)
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Real-Life Assessment of the Safety and Effectiveness of the New Tablet and Intravenous Formulations of Posaconazole in the Prophylaxis of Invasive Fungal Infections via Analysis of 343 Courses.
  • Posaconazole is the preferred mold-active azole for prophylaxis against invasive fungal infections (IFIs) in patients with hematological malignancy.

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  • [Copyright] Copyright © 2017 American Society for Microbiology.
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  • (PMID = 28507111.001).
  • [ISSN] 1098-6596
  • [Journal-full-title] Antimicrobial agents and chemotherapy
  • [ISO-abbreviation] Antimicrob. Agents Chemother.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; antifungal / cancer / hematological malignancy / posaconazole / prophylaxis
  •  go-up   go-down


11. Carr AC, Maggini S: Vitamin C and Immune Function. Nutrients; 2017 Nov 03;9(11)

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Vitamin C deficiency results in impaired immunity and higher susceptibility to infections.
  • In turn, infections significantly impact on vitamin C levels due to enhanced inflammation and metabolic requirements.
  • Furthermore, supplementation with vitamin C appears to be able to both prevent and treat respiratory and systemic infections.
  • In contrast, treatment of established infections requires significantly higher (gram) doses of the vitamin to compensate for the increased inflammatory response and metabolic demand.

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  • (PMID = 29099763.001).
  • [ISSN] 2072-6643
  • [Journal-full-title] Nutrients
  • [ISO-abbreviation] Nutrients
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Keywords] NOTNLM ; ascorbate / ascorbic acid / immune system / immunity / infection / lymphocytes / microbial killing / neutrophil function / vitamin C
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12. Dumanch KA, Holte L, O'Hollearn T, Walker E, Clark J, Oleson J: High Risk Factors Associated With Early Childhood Hearing Loss: A 3-Year Review. Am J Audiol; 2017 Jun 13;26(2):129-142

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Method: A retrospective data review was completed on 115,039 children born from 2010 to 2012.
  • Factors that placed children at the highest risk of congenital hearing impairment were neurodegenerative disorders, syndromes, and congenital infections.

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  • (PMID = 28475714.001).
  • [ISSN] 1558-9137
  • [Journal-full-title] American journal of audiology
  • [ISO-abbreviation] Am J Audiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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13. Teweldemedhin M, Gebreyesus H, Atsbaha AH, Asgedom SW, Saravanan M: Bacterial profile of ocular infections: a systematic review. BMC Ophthalmol; 2017 Nov 25;17(1):212

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bacterial profile of ocular infections: a systematic review.
  • BACKGROUND: Bacteria are the major contributor of ocular infections worldwide.
  • Ocular infections, if left untreated, can damage the structures of the eye with possible blindness and visual impairments.
  • This work was aimed to review the bacterial profile of ocular infections.
  • RESULTS: As far as this review, Staphylococcus aureus, Coagulase negative Staphylococci, Streptococcus pneumoniae and Pseudomonas aeruginosa are the leading isolates in ocular infections.
  • CONCLUSION: Gram positive bacteria are the major contributor of bacterial ocular infections.
  • To mitigate the burden of bacterial ocular infections, physicians should regard on risk reduction and comply with etiologic approach of diagnosis.

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  • (PMID = 29178851.001).
  • [ISSN] 1471-2415
  • [Journal-full-title] BMC ophthalmology
  • [ISO-abbreviation] BMC Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Bacterial profile / Ocular infection / Review
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14. Jeger V, Pop R, Forudastan F, Barras JP, Zuber M, Piso RJ: Is there a role for procalcitonin in differentiating uncomplicated and complicated diverticulitis in order to reduce antibiotic therapy? A prospective diagnostic cohort study. Swiss Med Wkly; 2017 Nov 29;147:w14555

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Biomarkers could help to guide antibiotic therapy as this approach has been shown to be effective for acute respiratory infections.
  • RESULTS: 115 patients were included for analysis.

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  • (PMID = 29185246.001).
  • [ISSN] 1424-3997
  • [Journal-full-title] Swiss medical weekly
  • [ISO-abbreviation] Swiss Med Wkly
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
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15. Dixit A, Tanaka A, Greer JM, Donnelly S: Novel Therapeutics for Multiple Sclerosis Designed by Parasitic Worms. Int J Mol Sci; 2017 Oct 13;18(10)

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The evolutionary response to endemic infections with parasitic worms (helminth) was the development of a distinct regulatory immune profile arising from the need to encapsulate the helminths while simultaneously repairing tissue damage.

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  • (PMID = 29027962.001).
  • [ISSN] 1422-0067
  • [Journal-full-title] International journal of molecular sciences
  • [ISO-abbreviation] Int J Mol Sci
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Keywords] NOTNLM ; environmental factors / helminth parasites / immune modulation / innate immunity / multiple sclerosis / old friend’s hypothesis
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16. Turhan O, Ozhak-Baysan B, Zaragoza O, Er H, Sarıtas ZE, Ongut G, Ogunc D, Colak D, Cuenca-Estrella M: Evaluation of MALDI-TOF-MS for the Identification of Yeast Isolates Causing Bloodstream Infection. Clin Lab; 2017 04 01;63(4):699-703

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Infections due to Candida species are major causes of morbidity and mortality in humans, causing a diverse spectrum of clinical disease ranging from superficial and mucosal infections to invasive disease.
  • The aim of this study was to assess the performance of the matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) system for the correct and rapid identification of yeast isolates causing bloodstream infection.
  • METHODS: Between January 2014 and January 2015, a total of 117 yeast like organisms isolated from blood culture samples of 117 episodes from 102 patients who had blood stream infections were included in the study.
  • RESULTS: One hundred and seventeen yeast isolates including 115 Candida spp and two non-Candida yeasts were analysed.
  • The Biotyper correctly identified 115 (98.3%) isolates to the genus level and 102 (87.2%) isolates to the species level using the manufacturer's recommended cutoff scores.
  • Early identification with MALDI-TOF MS would save time for determination of antifungal susceptibility and proper treatment strategy.

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  • (PMID = 28397475.001).
  • [ISSN] 1433-6510
  • [Journal-full-title] Clinical laboratory
  • [ISO-abbreviation] Clin. Lab.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antifungal Agents
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17. Datta P, Gupta V, Mohi GK, Chander J, Janmeja AK: &lt;i&gt;Lactobacillus coryniformis&lt;/i&gt; Causing Pulmonary Infection in a Patient with Metastatic Small Cell Carcinoma: Case Report and Review of Literature on &lt;i&gt;Lactobacillus&lt;/i&gt; Pleuro-Pulmonary Infections. J Clin Diagn Res; 2017 Feb;11(2):DE01-DE05

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] <i>Lactobacillus coryniformis</i> Causing Pulmonary Infection in a Patient with Metastatic Small Cell Carcinoma: Case Report and Review of Literature on <i>Lactobacillus</i> Pleuro-Pulmonary Infections.
  • Due to its low virulence these bacteria are known to cause opportunistic infections.
  • We report a case of <i>Lactobacillus coryniformis</i> pleuro-pulmonary infection and review 14 previously reported cases of lactobacilli causing pleuro-pulmonary infections.
  • Our patient had small cell carcinoma with metastasis.
  • The diagnosis of these infections requires both microbiologist and clinical correlation to rule out contamination.

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  • (PMID = 28384865.001).
  • [ISSN] 2249-782X
  • [Journal-full-title] Journal of clinical and diagnostic research : JCDR
  • [ISO-abbreviation] J Clin Diagn Res
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] India
  • [Keywords] NOTNLM ; Ampicillin / Bacteraemia / Commensals / Immunosuppression
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18. DeCicco RePass MA, Chen Y, Lin Y, Zhou W, Kaplan DL, Ward HD: Novel Bioengineered Three-Dimensional Human Intestinal Model for Long-Term Infection of Cryptosporidium parvum. Infect Immun; 2017 Mar;85(3)
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We found that <i>C. parvum</i> infected and developed in this tissue model for at least 17 days, the extent of the study time used in the present study.
  • Contents from infected scaffolds could be transferred to fresh scaffolds to establish new infections for at least three rounds.

  • MedlinePlus Health Information. consumer health - Cryptosporidiosis.
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  • [Copyright] Copyright © 2017 American Society for Microbiology.
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  • (PMID = 28052996.001).
  • [ISSN] 1098-5522
  • [Journal-full-title] Infection and immunity
  • [ISO-abbreviation] Infect. Immun.
  • [Language] eng
  • [Grant] United States / NIBIB NIH HHS / EB / P41 EB002520; United States / NIAID NIH HHS / AI / T32 AI007077
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; 3D model / Cryptosporidium / in vitro culture / intestinal epithelial cells
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19. Prabhu VS, Solomkin JS, Medic G, Foo J, Borse RH, Kauf T, Miller B, Sen SS, Basu A: Cost-effectiveness of ceftolozane/tazobactam plus metronidazole versus piperacillin/tazobactam as initial empiric therapy for the treatment of complicated intra-abdominal infections based on pathogen distributions drawn from national surveillance data in the United States. Antimicrob Resist Infect Control; 2017;6:107

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cost-effectiveness of ceftolozane/tazobactam plus metronidazole versus piperacillin/tazobactam as initial empiric therapy for the treatment of complicated intra-abdominal infections based on pathogen distributions drawn from national surveillance data in the United States.
  • BACKGROUND: The prevalence of antimicrobial resistance among gram-negative pathogens in complicated intra-abdominal infections (cIAIs) has increased.
  • RESULTS: Our model results, with baseline resistance levels from the PACTS database, indicated that ceftolozane/tazobactam + metronidazole dominated piperacillin/tazobactam, with lower costs ($44,226/patient vs. $44,811/patient respectively) and higher QALYs (12.85/patient vs. 12.70/patient, respectively).

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  • (PMID = 29090091.001).
  • [ISSN] 2047-2994
  • [Journal-full-title] Antimicrobial resistance and infection control
  • [ISO-abbreviation] Antimicrob Resist Infect Control
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Ceftolozane / Cost-effectiveness analysis / Drug resistance / Intraabdominal infections / Piperacillin / Tazobactam / United States
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20. Roele ED, Timmer VCML, Vaassen LAA, van Kroonenburgh AMJL, Postma AA: Dual-Energy CT in Head and Neck Imaging. Curr Radiol Rep; 2017;5(5):19

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Moreover, it can be helpful in imaging of infections and inflammation and parathyroid imaging as supplementary reconstructions can be obtained at lower or equal radiation dose compared with conventional single energy scanning.

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  • (PMID = 28435761.001).
  • [ISSN] 2167-4825
  • [Journal-full-title] Current radiology reports
  • [ISO-abbreviation] Curr Radiol Rep
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Dual-energy CT / Head and neck cancer / Lymph node imaging / Metal artifact reduction / Parathyroid adenoma / Spectral CT
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21. Park J, Ramanathan R, Pham L, Woodrow KA: Chitosan enhances nanoparticle delivery from the reproductive tract to target draining lymphoid organs. Nanomedicine; 2017 Aug;13(6):2015-2025
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • These observations indicate that chitosan may have great potential as an adjuvant for both local and systemic protective immunity against viral infections in the FRT.

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  • [Copyright] Copyright © 2017 Elsevier Inc. All rights reserved.
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  • (PMID = 28435136.001).
  • [ISSN] 1549-9642
  • [Journal-full-title] Nanomedicine : nanotechnology, biology, and medicine
  • [ISO-abbreviation] Nanomedicine
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / DP2 HD075703; United States / NIAID NIH HHS / AI / R21 AI094412; United States / NIAID NIH HHS / AI / R33 AI094412; United States / NIAID NIH HHS / AI / R56 AI074661
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  • [Keywords] NOTNLM ; Chitosan / Draining lymph node / Mucosal delivery / Nanoparticle / Reproductive tract
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22. Toth K, Spencer JF, Ying B, Tollefson AE, Wold WSM: HAdV-C6 Is a More Relevant Challenge Virus than HAdV-C5 for Testing Antiviral Drugs with the Immunosuppressed Syrian Hamster Model. Viruses; 2017 Jun 13;9(6)
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Adenovirus infections of immunocompromised patients can cause a severe multi-organ disease that often results in the patients' death.
  • Presently, there are no drugs specifically approved to treat adenovirus infections, and clinicians resort to the off-label use of antivirals that are approved to treat other DNA virus infections, most frequently cidofovir (CDV).
  • CDV, however, has considerable nephrotoxicity, thus it is recommended only for the most severe cases of adenovirus infections.
  • Further, we show for the first time that VGCV, and to a lesser extent CDV, can be used to treat respiratory adenovirus infections in the hamster model.
  • These results extend the utility of the hamster model, and demonstrate the efficacy of two drugs available for clinicians to treat adenovirus infections.

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  • (PMID = 28608847.001).
  • [ISSN] 1999-4915
  • [Journal-full-title] Viruses
  • [ISO-abbreviation] Viruses
  • [Language] eng
  • [Grant] United States / NIAID NIH HHS / AI / HHSN272201000021C; United States / NIAID NIH HHS / AI / HHSN272201000021I
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Keywords] NOTNLM ; adenovirus / animal model / antiviral / hamster
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23. Vimal A, Pal D, Tripathi T, Kumar A: Eucalyptol, sabinene and cinnamaldehyde: potent inhibitors of salmonella target protein L-asparaginase. 3 Biotech; 2017 Aug;7(4):258

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The amino acid residues involved in interactions inside the binding pocket are threonine 115 and threonine 35.
  • The results suggest they could be safe alternatives of chemical compounds to treat infections and combat multidrug-resistant bacteria.

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  • [ISSN] 2190-572X
  • [Journal-full-title] 3 Biotech
  • [ISO-abbreviation] 3 Biotech
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Keywords] NOTNLM ; Antimicrobial / L-Asparaginase / Pathogenicity / S. typhimurium / Spices
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24. Fan Y, Wang T, Koehler AV, Hu M, Gasser RB: Molecular investigation of Cryptosporidium and Giardia in pre- and post-weaned calves in Hubei Province, China. Parasit Vectors; 2017 Oct 25;10(1):519

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cattle, particularly calves, carrying these protists can be significant reservoirs for human infections and disease.

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  • (PMID = 29070070.001).
  • [ISSN] 1756-3305
  • [Journal-full-title] Parasites & vectors
  • [ISO-abbreviation] Parasit Vectors
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Calves / China / Cryptosporidium / Giardia / Nuclear ribosomal RNA genes / PCR-based sequencing
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25. Henneberger A, Ertl-Wagner B, Reiser M, Gürkov R, Flatz W: Morphometric evaluation of facial and vestibulocochlear nerves using magnetic resonance imaging: comparison of Menière's disease ears with normal hearing ears. Eur Arch Otorhinolaryngol; 2017 Aug;274(8):3029-3039
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ann Otol Rhinol Laryngol Suppl 81:26-31, 3; Kariya, Otol Neurotol Off Publ Am Otol Soc Am Neurotol Soc Eur Acad Otol Neurotol 28(8):1063-1068, 4; Megerian Laryngoscope 115(9):1525-1535, 5) but this has yet to be confirmed.
  • The exact pathophysiological mechanisms involved such as viral infections, autoimmune processes, genetic predisposition, cellular apoptosis, and oxidative stress are still not clear.

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  • (PMID = 28584970.001).
  • [ISSN] 1434-4726
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Keywords] NOTNLM ; 3 Tesla / 3D-GE-sequence / CISS / Diameter / Facial nerve / Magnetic resonance imaging / Meniere’s disease / Morphometry / N. VII. / N. VIII / T2w / Vestibulocochlear nerve / cross-sectional area
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26. Ranjan A, Shaik S, Nandanwar N, Hussain A, Tiwari SK, Semmler T, Jadhav S, Wieler LH, Alam M, Colwell RR, Ahmed N: Comparative Genomics of &lt;i&gt;Escherichia coli&lt;/i&gt; Isolated from Skin and Soft Tissue and Other Extraintestinal Infections. MBio; 2017 Aug 15;8(4)
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparative Genomics of <i>Escherichia coli</i> Isolated from Skin and Soft Tissue and Other Extraintestinal Infections.
  • <i>Escherichia coli</i>, an intestinal Gram-negative bacterium, has been shown to be associated with a variety of diseases in addition to intestinal infections, such as urinary tract infections (UTIs), meningitis in neonates, septicemia, skin and soft tissue infections (SSTIs), and colisepticemia.
  • Thus, for nonintestinal infections, it is categorized as extraintestinal pathogenic <i>E. coli</i> (ExPEC).
  • It is also an opportunistic pathogen, causing cross infections, notably as an agent of zoonotic diseases.
  • However, comparative genomic data providing functional and genetic coordinates for ExPEC strains associated with these different types of infections have not proven conclusive.
  • Overall, the isolates from a variety of ExPEC infections demonstrated similar resistomes and virulomes and did not display any disease-specific functional or genetic coordinates.
  • <b>IMPORTANCE</b> Infections caused by extraintestinal pathogenic <i>E. coli</i> (ExPEC) are of global concern as they result in significant costs to health care facilities management.
  • In developing countries, such as India, skin and soft tissue infections (SSTIs) associated with <i>E. coli</i> are marginally addressed.

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  • [Copyright] Copyright © 2017 Ranjan et al.
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  • (PMID = 28811343.001).
  • [ISSN] 2150-7511
  • [Journal-full-title] mBio
  • [ISO-abbreviation] MBio
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Escherichia coli / genomics / sepsis
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27. Drinkall E, Wass MJ, Coffey TJ, Flynn RJ: A rapid IL-17 response to Cryptosporidium parvum in the bovine intestine. Vet Immunol Immunopathol; 2017 Sep;191:1-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Immunity develops after repeated infections but initial infections can be severe, highlighting the importance of early infection dynamics.
  • IL-17A accumulated over time peaking at 9h post-infection, with no effect of infection on IL-1β; antibiotics positively influenced IL-17A as higher levels were found in cultures with antibiotics.

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  • [Copyright] Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.
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  • (PMID = 28895860.001).
  • [ISSN] 1873-2534
  • [Journal-full-title] Veterinary immunology and immunopathology
  • [ISO-abbreviation] Vet. Immunol. Immunopathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Keywords] NOTNLM ; Biopsy / Bovine / Cryptosporidium parvum / IL-17A / Intestine / Villi
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28. Hashimoto A, Suto S, Horie K, Fukuda H, Nogi S, Iwata K, Tsuno H, Ogihara H, Kawakami M, Komiya A, Furukawa H, Matsui T, Tohma S: Incidence and Risk Factors for Infections Requiring Hospitalization, Including Pneumocystis Pneumonia, in Japanese Patients with Rheumatoid Arthritis. Int J Rheumatol; 2017;2017:6730812

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Incidence and Risk Factors for Infections Requiring Hospitalization, Including Pneumocystis Pneumonia, in Japanese Patients with Rheumatoid Arthritis.
  • Objective: Rheumatoid arthritis (RA) may be complicated by different infections, but risk factors for these are not fully elucidated.
  • Here, we assessed the incidence of and risk factors for infections requiring hospitalization (IRH) including pneumocystis pneumonia (PCP) in patients with RA.
  • Results: In a total of 9210 patient-years (2688 patients), there were 373 IRH (3.7/100 patient-years).
  • Respiratory tract infections were most frequent (<i>n</i> = 154, and additionally 16 PCP), followed by urinary tract infections (<i>n</i> = 50).
  • Use of methotrexate (5.7) was positively associated with PCP but negatively with total infections (0.7).
  • Additionally, functional disorders and higher RA disease activity were also related to total infections.
  • Conclusions: Risk factors for infection should be taken into account when deciding treatment for the individual RA patient.

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  • (PMID = 29181029.001).
  • [ISSN] 1687-9260
  • [Journal-full-title] International journal of rheumatology
  • [ISO-abbreviation] Int J Rheumatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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29. Velazquez-Hernandez N, Aguilar-Duran M, Perez-Alamos AR, Estrada-Martinez S, Salas-Pacheco JM, Sanchez-Anguiano LF, Sandoval-Carrillo AA, Lazalde-Medina B, Alvarado-Esquivel C: Lack of Association between Mannose-binding Lectin 2 Codons 54 and 57 Gene Polymorphisms and Cervicovaginal Infections in Mexican Women. Int J Biomed Sci; 2017 Jun;13(2):79-83
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lack of Association between Mannose-binding Lectin 2 Codons 54 and 57 Gene Polymorphisms and Cervicovaginal Infections in Mexican Women.
  • Some studies have assessed the association of the MBL2 gene polymorphisms with cervicovaginal infections (CVI); however, there is no information about this association in Mexican women.
  • MBL2 genotyping was performed by real-time polymerase chain reaction with Taqman probes.

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  • (PMID = 28824344.001).
  • [ISSN] 1550-9702
  • [Journal-full-title] International journal of biomedical science : IJBS
  • [ISO-abbreviation] Int J Biomed Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Cervicovaginal infections / MBL2 gene / codon 54 / codon 57
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30. Accardi R, Castaldi S, Marzullo A, Ronchi S, Laquintana D, Lusignani M: Prevention of healthcare associated infections: a descriptive study. Ann Ig; 2017 Mar-Apr;29(2):101-115
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prevention of healthcare associated infections: a descriptive study.
  • BACKGROUND: This study aims to verify whether there are, and to which degree, knowledge and adherence to guidelines on the prevention and control of healthcare associated infections by nursing staff. Study design.
  • The data collected concern, both for the knowledge and for the practice, the following macro-areas: a) Cleaning, disinfection and sterilization, b) Hand hygiene, c) Standard and isolation precautions, d) Prevention of catheter-related urinary tract infections, e) Prevention of catheter-related bacteremia, f) Prevention of surgical site infections, g) Prevention of respiratory tract infections.
  • CONCLUSION: Some knowledge gaps and differences with respect to adherence to best-practice principles for the prevention and control of healthcare associated infections was highlight by the present study.
  • [MeSH-minor] Adult. Catheter-Related Infections / prevention & control. Clinical Competence. Delivery of Health Care / standards. Female. Hand Hygiene / standards. Humans. Male. Middle Aged. Nurse's Role. Nursing / standards. Retrospective Studies. Surgical Wound Infection / prevention & control. Surveys and Questionnaires

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  • (PMID = 28244579.001).
  • [ISSN] 1120-9135
  • [Journal-full-title] Annali di igiene : medicina preventiva e di comunita
  • [ISO-abbreviation] Ann Ig
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Keywords] NOTNLM ; Adherence (major topic) / Guidelines (major topic) / Healthcare associated infections (major topic) / Knowledge (major topic) / Nurses (major topic)
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31. Kim GS, Lee KS, Park CK, Kang SK, Kim DW, Oh SG, Oh BS, Jung Y, Kim S, Yun JS, Song SY, Na KJ, Jeong IS, Ahn BH: Nosocomial Infection in Adult Patients Undergoing Veno-Arterial Extracorporeal Membrane Oxygenation. J Korean Med Sci; 2017 Apr;32(4):593-598

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Data on the frequency of nosocomial infections during extracorporeal membrane oxygenation (ECMO) in adult populations remain scarce.
  • We investigated the risk factors for nosocomial infections in adult patients undergoing venoarterial ECMO (VA-ECMO) support.
  • Mean patient age was 60.6 ± 14.3 years and 21 (34.4%) patients were female.
  • There were 18 nosocomial infections in 14 (23.0%) patients.
  • These included respiratory tract infections in 9 cases and bloodstream infections in a further 9.
  • Therefore, to avoid the development of nosocomial infections, strategies to shorten the length of ECMO support should be applied whenever possible.
  • [MeSH-minor] Adult. Aged. Creatinine / blood. Female. Gram-Negative Bacteria / isolation & purification. Humans. Incidence. Male. Middle Aged. Multivariate Analysis. Odds Ratio. Proportional Hazards Models. Respiratory Tract Infections / diagnosis. Respiratory Tract Infections / therapy. Risk Factors. Shock, Cardiogenic / etiology. Time Factors. Young Adult

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  • [Copyright] © 2017 The Korean Academy of Medical Sciences.
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  • (PMID = 28244284.001).
  • [ISSN] 1598-6357
  • [Journal-full-title] Journal of Korean medical science
  • [ISO-abbreviation] J. Korean Med. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] AYI8EX34EU / Creatinine
  • [Keywords] NOTNLM ; Extracorporeal Membrane Oxygenation Support / Infection
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32. Bloom K, Ely A, Arbuthnot P: A T7 Endonuclease I Assay to Detect Talen-Mediated Targeted Mutation of HBV cccDNA. Methods Mol Biol; 2017;1540:85-95

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The technology is being developed for the treatment of viral infections such as persistant hepatitis B virus (HBV).

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  • (PMID = 27975310.001).
  • [ISSN] 1940-6029
  • [Journal-full-title] Methods in molecular biology (Clifton, N.J.)
  • [ISO-abbreviation] Methods Mol. Biol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; HBV / Indels / T7EI / TALEN / cccDNA
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33. Panariello BHD, Klein MI, Pavarina AC, Duarte S: Inactivation of genes TEC1 and EFG1 in &lt;i&gt;Candida albicans&lt;/i&gt; influences extracellular matrix composition and biofilm morphology. J Oral Microbiol; 2017;9(1):1385372

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • <b>Background</b>: Infections caused by <i>Candida</i> spp. have been associated with formation of a biofilm, i.e. a complex microstructure of cells adhering to a surface and embedded within an extracellular matrix (ECM).

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  • (PMID = 29081917.001).
  • [ISSN] 2000-2297
  • [Journal-full-title] Journal of oral microbiology
  • [ISO-abbreviation] J Oral Microbiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Candida albicans / EFG1 / TEC1 / biofilm / extracellular matrix
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34. Amaral AJ, Andrade J, Foxall RB, Matoso P, Matos AM, Soares RS, Rocha C, Ramos CG, Tendeiro R, Serra-Caetano A, Guerra-Assunção JA, Santa-Marta M, Gonçalves J, Gama-Carvalho M, Sousa AE: miRNA profiling of human naive CD4 T cells links miR-34c-5p to cell activation and HIV replication. EMBO J; 2017 Feb 01;36(3):346-360
Genetic Alliance. consumer health - HIV.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Our results demonstrate, for the first time, the transcriptional up-regulation of miR-34c-5p in response to TCR stimulation in naive CD4 T cells.
  • The induction of this miR was further consistently found to be reduced by both HIV-1 and HIV-2 infections.

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  • [Copyright] © 2016 The Authors.
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  • (PMID = 27993935.001).
  • [ISSN] 1460-2075
  • [Journal-full-title] The EMBO journal
  • [ISO-abbreviation] EMBO J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / MIRN34 microRNA, human; 0 / MicroRNAs; 0 / Receptors, Antigen, T-Cell
  • [Keywords] NOTNLM ; HIV‐1 / HIV‐2 / T‐cell activation / miR‐34c‐5p / naive CD4 T cells
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35. Ezzi O, Bouafia N, Mahjoub M, Ben Cheikh A, Bannour W, Helali R, Bayar H, Nouira A, Njah M: [Perceptions of a healthcare-associated infections reporting system in a Tunisian university hospital]. Sante Publique; 2017 Mar 06;29(1):115-123

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Perceptions of a healthcare-associated infections reporting system in a Tunisian university hospital].
  • [Transliterated title] Perceptions d’un système de signalement des infections associées aux soins dans un hôpital universitaire tunisien.
  • Objective: The implementation of a healthcare-associated infections reporting system is a principal component of infection control and quality improvement policies in healthcare institutions.
  • This study was designed to determine the perceptions of health professionals concerning implementation of a healthcare-associated infections reporting system and to analyse factors influencing these perceptions.Methods: A descriptive cross-sectional study conducted in 2012 using a predefined, pre-tested and self-administered questionnaire in 380 health professionals working in 16 different departments of Farhat Hached University Hospital, Tunisia.Results: The majority of respondents (71.8%) reported that no healthcare-associated infections surveillance procedure had been implemented in their departments.
  • However, most respondents (93%) recognised the value of implementation of a healthcare-associated infections reporting system in order to provide them with corrective actions (77%), to support the investigation of epidemic and emerging phenomena (49%) and to share experiences about the prevalence of healthcare-associated infections and their risk factors (44%).Conclusion: Staff training and development of a regulatory framework are essential to implementation and correct functioning of a healthcare-associated infections reporting system.

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  • (PMID = 28737318.001).
  • [ISSN] 0995-3914
  • [Journal-full-title] Sante publique (Vandoeuvre-les-Nancy, France)
  • [ISO-abbreviation] Sante Publique
  • [Language] fre
  • [Publication-type] Journal Article
  • [Publication-country] France
  • [Keywords] NOTNLM ; cross-infections (major topic) / epidemiological monitoring (major topic) / reporting (major topic) / prevention (major topic) / Tunisia (major topic)
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36. Agarwal R, Mohapatra S, Rath GP, Kapil A: Active Surveillance of Health Care Associated Infections in Neurosurgical Patients. J Clin Diagn Res; 2017 Jul;11(7):DC01-DC04

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Active Surveillance of Health Care Associated Infections in Neurosurgical Patients.
  • INTRODUCTION: Health Care Associated Infections (HCAI) are frequent complications in neurosurgery.
  • RESULTS: A total of 330 patients with 4054 patient-days were analysed for HCAI.
  • The overall rate of HCAI was 6.67% and 5.42 per 1000 patient-days.

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37. Marvin SA: The Immune Response to Astrovirus Infection. Viruses; 2016 12 30;9(1)

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Studies from humans and animals suggest that adaptive immunity is important in restricting classic and novel astrovirus infections, while studies from animal models and cell culture systems suggest that an innate immune system plays a role in limiting astrovirus replication.
  • [MeSH-major] Astroviridae / immunology. Astroviridae Infections / immunology

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  • (PMID = 28042824.001).
  • [ISSN] 1999-4915
  • [Journal-full-title] Viruses
  • [ISO-abbreviation] Viruses
  • [Language] eng
  • [Publication-type] Journal Article; Review; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
  • [Keywords] NOTNLM ; adaptive immunity (major topic) / astrovirus infection (major topic) / astrovirus replication (major topic) / immune response (major topic) / innate immunity (major topic) / type I interferon (major topic)
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38. Minutti CM, Drube S, Blair N, Schwartz C, McCrae JC, McKenzie AN, Kamradt T, Mokry M, Coffer PJ, Sibilia M, Sijts AJ, Fallon PG, Maizels RM, Zaiss DM: Epidermal Growth Factor Receptor Expression Licenses Type-2 Helper T Cells to Function in a T Cell Receptor-Independent Fashion. Immunity; 2017 Oct 17;47(4):710-722.e6
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Gastro-intestinal helminth infections trigger the release of interleukin-33 (IL-33), which induces type-2 helper T cells (Th2 cells) at the site of infection to produce IL-13, thereby contributing to host resistance in a T cell receptor (TCR)-independent manner.
  • [MeSH-minor] Amphiregulin / immunology. Amphiregulin / metabolism. Animals. Cell Line. Cells, Cultured. Gene Expression / genetics. Gene Expression / immunology. Gene Expression Profiling / methods. HEK293 Cells. Humans. MAP Kinase Signaling System / immunology. Mice, Inbred C57BL. Mice, Knockout. Mice, Transgenic. Nematospiroides dubius / immunology. Nematospiroides dubius / physiology. Nocardia / immunology. Nocardia / physiology. Nocardia Infections / immunology. Nocardia Infections / metabolism. Nocardia Infections / microbiology. Reverse Transcriptase Polymerase Chain Reaction. Strongylida Infections / immunology. Strongylida Infections / metabolism. Strongylida Infections / parasitology

  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
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  • [Copyright] Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.
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  • (PMID = 29045902.001).
  • [ISSN] 1097-4180
  • [Journal-full-title] Immunity
  • [ISO-abbreviation] Immunity
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Amphiregulin; 0 / Interleukin-13; 0 / Interleukin-33; 0 / Receptors, Antigen, T-Cell; EC 2.7.10.1 / Receptor, Epidermal Growth Factor
  • [Keywords] NOTNLM ; TCR-independent IL-13 secretion / cytokine signaling / gastro-intestinal helminth infections / interleukin-13 / interleukin-33 / type-2 helper T cells
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39. Agrawal A: Dendritic Cell-Airway Epithelial Cell Cross-Talk Changes with Age and Contributes to Chronic Lung Inflammatory Diseases in the Elderly. Int J Mol Sci; 2017 Jun 06;18(6)

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The interaction between DCs and AECs plays a crucial role in lung immunity at homeostasis and during infections.

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  • (PMID = 28587289.001).
  • [ISSN] 1422-0067
  • [Journal-full-title] International journal of molecular sciences
  • [ISO-abbreviation] Int J Mol Sci
  • [Language] eng
  • [Grant] United States / NIA NIH HHS / AG / R01 AG045216; United States / NCATS NIH HHS / TR / UL1 TR000153
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Keywords] NOTNLM ; age / airway epithelial cells / crosstalk / dendritic cells / human / inflammation
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40. Maier M, Takano T, Sapir-Pichhadze R: Changing Paradigms in the Management of Rejection in Kidney Transplantation: Evolving From Protocol-Based Care to the Era of P4 Medicine. Can J Kidney Health Dis; 2017;4:2054358116688227

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Pharmacogenomics are discussed as means to facilitate personalized immunosuppression regimens and promotion of active patient participation as a means to improve adherence.
  • P4 medicine, however, should more broadly address health concerns in kidney transplant recipients, including competing outcomes such as infections, malignancies, and cardiovascular disease.

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  • (PMID = 28270929.001).
  • [Journal-full-title] Canadian journal of kidney health and disease
  • [ISO-abbreviation] Can J Kidney Health Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; adherence / biomarkers / immune competency / pharmacogenomics / surveillance
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41. Gifford J, Vaeth E, Richards K, Siddiqui T, Gill C, Wilson L, DeLisle S: Decision support during electronic prescription to stem antibiotic overuse for acute respiratory infections: a long-term, quasi-experimental study. BMC Infect Dis; 2017 Jul 31;17(1):528
Hazardous Substances Data Bank. AZITHROMYCIN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Decision support during electronic prescription to stem antibiotic overuse for acute respiratory infections: a long-term, quasi-experimental study.
  • BACKGROUND: Interventions to support decision-making can reduce inappropriate antibiotic use for acute respiratory infections (ARI), but they may not be sustainable.
  • The objective of the study is to evaluate the long-term effectiveness of a clinical decision-support system (CDSS) interposed at the time of electronic (e-) prescriptions for selected antibiotics.
  • For fluoroquinolones, guideline concordance decreased from 88.6% (39 of 44 visits) to 51.3% (59 of 115 visits), pre- vs. post-withdrawal periods (p < 0.005).
  • Concordance did not change between those same time periods for antibiotics that were never subjected to the intervention ("All Other Antibiotics").
  • CONCLUSIONS: A CDSS interposed at the time of e-prescription of selected antibiotics can shift their use toward ARI treatment guidelines, and this effect can be maintained over the long term as long as the CDSS remains in place.
  • [MeSH-major] Anti-Bacterial Agents / therapeutic use. Decision Support Systems, Clinical. Electronic Prescribing / statistics & numerical data. Prescription Drug Overuse / prevention & control. Respiratory Tract Infections / drug therapy

  • MedlinePlus Health Information. consumer health - Antibiotics.
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  • (PMID = 28760143.001).
  • [ISSN] 1471-2334
  • [Journal-full-title] BMC infectious diseases
  • [ISO-abbreviation] BMC Infect. Dis.
  • [Language] eng
  • [Publication-type] Journal Article; Observational Study
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 0 / Fluoroquinolones; 83905-01-5 / Azithromycin; L4618BD7KJ / gatifloxacin
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42. Cheng K, Van de Waal DB, Niu XY, Zhao YJ: Combined Effects of Elevated &lt;i&gt;p&lt;/i&gt;CO&lt;sub&gt;2&lt;/sub&gt; and Warming Facilitate Cyanophage Infections. Front Microbiol; 2017;8:1096

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Combined Effects of Elevated <i>p</i>CO<sub>2</sub> and Warming Facilitate Cyanophage Infections.
  • At several time points during the 1 year period, and upon re-exposure, we measured various infection characteristics of it associated cyanophage PP, including the burst size, latent period, lytic cycle and the efficiency of plaquing (EOP).
  • Our results demonstrate that adaptation but particularly physiological acclimation to climate change conditions favored viral infections, while limited host plasticity and slow adaptation after re-exposure to control conditions impeded host biomass build-up and viral infections.

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  • (PMID = 28659906.001).
  • [ISSN] 1664-302X
  • [Journal-full-title] Frontiers in microbiology
  • [ISO-abbreviation] Front Microbiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Keywords] NOTNLM ; EOP / climate change / common garden experiment / cyanobacterial virus / infectivity / one-step growth curve
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43. Slaats J, Ten Oever J, van de Veerdonk FL, Netea MG: IL-1β/IL-6/CRP and IL-18/ferritin: Distinct Inflammatory Programs in Infections. PLoS Pathog; 2016 Dec;12(12):e1005973
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] IL-1β/IL-6/CRP and IL-18/ferritin: Distinct Inflammatory Programs in Infections.
  • The host inflammatory response against infections is characterized by the release of pro-inflammatory cytokines and acute-phase proteins, driving both innate and adaptive arms of the immune response.
  • This review discusses the profiles of acute-phase proteins and circulating cytokines encountered in viral and bacterial infections.
  • We also propose a model in which the inflammatory response to viral (IL-18/ferritin) and bacterial (IL-6/CRP) infections presents with specific plasma patterns of immune biomarkers.
  • [MeSH-major] Acute-Phase Proteins / immunology. Bacterial Infections / immunology. Cytokines / immunology. Inflammation / immunology. Virus Diseases / immunology

  • MedlinePlus Health Information. consumer health - Bacterial Infections.
  • MedlinePlus Health Information. consumer health - Viral Infections.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
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  • (PMID = 27977798.001).
  • [ISSN] 1553-7374
  • [Journal-full-title] PLoS pathogens
  • [ISO-abbreviation] PLoS Pathog.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Acute-Phase Proteins; 0 / Cytokines; 0 / Inflammation Mediators; 0 / Interleukin-18; 0 / Interleukin-1beta; 0 / Interleukin-6; 9007-41-4 / C-Reactive Protein; 9007-73-2 / Ferritins
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44. Montespan C, Wiethoff CM, Wodrich H: A Small Viral PPxY Peptide Motif To Control Antiviral Autophagy. J Virol; 2017 Sep 15;91(18)

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This mechanism, also termed selective autophagy, is well characterized for invasive bacteria but remains poorly documented for viral infections.

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  • [Copyright] Copyright © 2017 American Society for Microbiology.
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  • (PMID = 28659475.001).
  • [ISSN] 1098-5514
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Peptides
  • [Keywords] NOTNLM ; adenoviruses / autophagy / innate immunity / virus entry
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45. Fonseca LL, Joyner CJ, MaHPIC Consortium, Galinski MR, Voit EO: A model of Plasmodium vivax concealment based on Plasmodium cynomolgi infections in Macaca mulatta. Malar J; 2017 Sep 18;16(1):375

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A model of Plasmodium vivax concealment based on Plasmodium cynomolgi infections in Macaca mulatta.
  • The total parasite biomass during infections is correlated with the severity of disease but not necessarily quantified accurately by microscopy.
  • METHODS: Time series data tracking the longitudinal development of parasitaemia in five Macaca mulatta infected with P. cynomolgi were used to design a computational model quantifying iRBCs that circulate in the blood versus those that are not detectable and are termed here as 'concealed'.
  • This inference has implications for understanding vivax biology and pathogenesis and stresses the importance of considering a concealed parasite reservoir with regard to vivax epidemiology and the quantification and treatment of P. vivax infections.

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  • (PMID = 28923058.001).
  • [ISSN] 1475-2875
  • [Journal-full-title] Malaria journal
  • [ISO-abbreviation] Malar. J.
  • [Language] eng
  • [Grant] United States / NIAID NIH HHS / AI / HHSN272201200031C; United States / NIH HHS / OD / P51 OD011132
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Host–pathogen interactions / Malaria / Mathematical model / Parasite dynamics / Plasmodium falciparum / Sequestration / Systems biology
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46. Bilgic HB, Bakırcı S, Kose O, Unlu AH, Hacılarlıoglu S, Eren H, Weir W, Karagenc T: Prevalence of tick-borne haemoparasites in small ruminants in Turkey and diagnostic sensitivity of single-PCR and RLB. Parasit Vectors; 2017 Apr 27;10(1):211

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The diagnostic sensitivity of these two approaches was then compared in terms of their ability to detect single species and mixed infections.
  • OT1, T. luwenshuni and T. uilenbergi in Turkey was revealed for the first time while the presence of Babesia motasi, B. crassa and T. separata in Turkish small ruminants was confirmed using molecular methods.
  • More than 80% of the mixed infections contained T. ovis and/or A. ovis.
  • The RLB approach was found to be capable of detecting mixed infections with species such as Theileria sp.
  • However, the latter approach was still capable of identifying a high proportion of individuals containing mixed-species infections.

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  • (PMID = 28449722.001).
  • [ISSN] 1756-3305
  • [Journal-full-title] Parasites & vectors
  • [ISO-abbreviation] Parasit Vectors
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Goat / Prevalence / RLB / Sheep / Species-specific PCR / Tick-borne pathogens / Turkey
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47. Kittayapong P, Olanratmanee P, Maskhao P, Byass P, Logan J, Tozan Y, Louis V, Gubler DJ, Wilder-Smith A: Mitigating Diseases Transmitted by Aedes Mosquitoes: A Cluster-Randomised Trial of Permethrin-Impregnated School Uniforms. PLoS Negl Trop Dis; 2017 Jan;11(1):e0005197
Hazardous Substances Data Bank. PERMETHRIN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The primary endpoint was laboratory-confirmed dengue infections.
  • In the control schools, 24/641 (3.7%) and in the intervention schools 33/1,014 (3.3%) students had evidence of new dengue infections during one school term (5 months).
  • There was no significant difference in proportions of students having incident dengue infections between the intervention and control schools, with adjustment for clustering by school.
  • However, there was no serological evidence of protection against dengue infections over the five months school term, best explained by the rapid washing-out of permethrin after 4 washes.

  • MedlinePlus Health Information. consumer health - Chikungunya.
  • MedlinePlus Health Information. consumer health - Dengue.
  • MedlinePlus Health Information. consumer health - Zika Virus.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
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  • (PMID = 28103255.001).
  • [ISSN] 1935-2735
  • [Journal-full-title] PLoS neglected tropical diseases
  • [ISO-abbreviation] PLoS Negl Trop Dis
  • [Language] eng
  • [Databank-accession-numbers] ClinicalTrials.gov/ NCT01563640
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] United States
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48. Bertrand MJM, Favreau M, De Bruyne E, Maes K, De Veirman K, Radwanska M, Samali A, Magez S, Vanderkerken K, De Trez C: Experimental African trypanosome infection suppresses the development of multiple myeloma in mice by inducing intrinsic apoptosis of malignant plasma cells. Oncotarget; 2017 Aug 08;8(32):52016-52025

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Together, these results demonstrate that trypanosome infections can interfere with MM development by suppressing endogenous UPR activation and promoting intrinsic apoptosis.

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  • (PMID = 28881710.001).
  • [ISSN] 1949-2553
  • [Journal-full-title] Oncotarget
  • [ISO-abbreviation] Oncotarget
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; T. brucei / multiple myeloma
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49. Sel