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1. Souquette A, Frere J, Smithey M, Sauce D, Thomas PG: A constant companion: immune recognition and response to cytomegalovirus with aging and implications for immune fitness. Geroscience; 2017 Jun;39(3):293-303

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Understanding how CMV contributes to shaping "baseline" immunity has important implications for a host's ability to mount effective responses to diverse infections and vaccination.

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  • (PMID = 28647907.001).
  • [ISSN] 2509-2723
  • [Journal-full-title] GeroScience
  • [ISO-abbreviation] Geroscience
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Keywords] NOTNLM ; Aging / Coinfection / Cytomegalovirus / Herpesvirus / Immune fitness / Immune response
  •  go-up   go-down


2. Jaishankar D, Shukla D: Genital Herpes: Insights into Sexually Transmitted Infectious Disease. Microb Cell; 2016 Jun 27;3(9):438-450

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Etiology, transmission and protection: Herpes simplex virus-2 (HSV-2) is a leading cause of sexually transmitted infections with recurring manifestations throughout the lifetime of infected hosts.
  • Pathology/Symptomatology: Primary and recurrent infections result in lesions and inflammation around the genital area and the latter accounts for majority of genital herpes instances.
  • Immunocompromised patients including neonates are susceptible to additional systemic infections including debilitating consequences of nervous system inflammation.

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  • (PMID = 28357380.001).
  • [ISSN] 2311-2638
  • [Journal-full-title] Microbial cell (Graz, Austria)
  • [ISO-abbreviation] Microb Cell
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Austria
  • [Keywords] NOTNLM ; antivirals / herpes simplex virus / viral glycoproteins / viral latency / virus entry
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3. Velazquez-Hernandez N, Aguilar-Duran M, Perez-Alamos AR, Estrada-Martinez S, Salas-Pacheco JM, Sanchez-Anguiano LF, Sandoval-Carrillo AA, Lazalde-Medina B, Alvarado-Esquivel C: Lack of Association between Mannose-binding Lectin 2 Codons 54 and 57 Gene Polymorphisms and Cervicovaginal Infections in Mexican Women. Int J Biomed Sci; 2017 Jun;13(2):79-83
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Lack of Association between Mannose-binding Lectin 2 Codons 54 and 57 Gene Polymorphisms and Cervicovaginal Infections in Mexican Women.
  • Some studies have assessed the association of the MBL2 gene polymorphisms with cervicovaginal infections (CVI); however, there is no information about this association in Mexican women.
  • MBL2 genotyping was performed by real-time polymerase chain reaction with Taqman probes.

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  • (PMID = 28824344.001).
  • [ISSN] 1550-9702
  • [Journal-full-title] International journal of biomedical science : IJBS
  • [ISO-abbreviation] Int J Biomed Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Cervicovaginal infections / MBL2 gene / codon 54 / codon 57
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4. Ranjan A, Shaik S, Nandanwar N, Hussain A, Tiwari SK, Semmler T, Jadhav S, Wieler LH, Alam M, Colwell RR, Ahmed N: Comparative Genomics of <i>Escherichia coli</i> Isolated from Skin and Soft Tissue and Other Extraintestinal Infections. MBio; 2017 Aug 15;8(4)
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparative Genomics of <i>Escherichia coli</i> Isolated from Skin and Soft Tissue and Other Extraintestinal Infections.
  • <i>Escherichia coli</i>, an intestinal Gram-negative bacterium, has been shown to be associated with a variety of diseases in addition to intestinal infections, such as urinary tract infections (UTIs), meningitis in neonates, septicemia, skin and soft tissue infections (SSTIs), and colisepticemia.
  • Thus, for nonintestinal infections, it is categorized as extraintestinal pathogenic <i>E. coli</i> (ExPEC).
  • It is also an opportunistic pathogen, causing cross infections, notably as an agent of zoonotic diseases.
  • However, comparative genomic data providing functional and genetic coordinates for ExPEC strains associated with these different types of infections have not proven conclusive.
  • Overall, the isolates from a variety of ExPEC infections demonstrated similar resistomes and virulomes and did not display any disease-specific functional or genetic coordinates.
  • <b>IMPORTANCE</b> Infections caused by extraintestinal pathogenic <i>E. coli</i> (ExPEC) are of global concern as they result in significant costs to health care facilities management.
  • In developing countries, such as India, skin and soft tissue infections (SSTIs) associated with <i>E. coli</i> are marginally addressed.

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  • [Copyright] Copyright © 2017 Ranjan et al.
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  • (PMID = 28811343.001).
  • [ISSN] 2150-7511
  • [Journal-full-title] mBio
  • [ISO-abbreviation] MBio
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Escherichia coli / genomics / sepsis
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5. Russell CD, Unger SA, Walton M, Schwarze J: The Human Immune Response to Respiratory Syncytial Virus Infection. Clin Microbiol Rev; 2017 Apr;30(2):481-502
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  • Respiratory syncytial virus (RSV) is an important etiological agent of respiratory infections, particularly in children.
  • [MeSH-major] Respiratory Syncytial Virus Infections / immunology

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  • [Copyright] Copyright © 2017 American Society for Microbiology.
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  • (PMID = 28179378.001).
  • [ISSN] 1098-6618
  • [Journal-full-title] Clinical microbiology reviews
  • [ISO-abbreviation] Clin. Microbiol. Rev.
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / G0901697; United Kingdom / Medical Research Council / / MR/K002589/1
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cytokines
  • [Keywords] NOTNLM ; immunology / respiratory syncytial virus
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6. Tracy KE, Baumgarth N: &lt;i&gt;Borrelia burgdorferi&lt;/i&gt; Manipulates Innate and Adaptive Immunity to Establish Persistence in Rodent Reservoir Hosts. Front Immunol; 2017;8:116

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • <i>Borrelia burgdorferi</i> sensu lato species complex is capable of establishing persistent infections in a wide variety of species, particularly rodents.

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  • (PMID = 28265270.001).
  • [ISSN] 1664-3224
  • [Journal-full-title] Frontiers in immunology
  • [ISO-abbreviation] Front Immunol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Keywords] NOTNLM ; complement inhibition / germinal center / immune evasion / immune exhaustion / lyme disease / persistent infection
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7. Anderson T, Coughlan E, Werno A: Mycoplasma genitalium Macrolide and Fluoroquinolone Resistance Detection and Clinical Implications in a Selected Cohort in New Zealand. J Clin Microbiol; 2017 Nov;55(11):3242-3248

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • <i>Mycoplasma genitalium</i> has been associated with infections of the genitourinary tract, and prevalence is secondary to <i>Chlamydia trachomatis</i> The clinical observation of increasing treatment failure indicating antibiotic resistance, especially in cases of recurrent urethritis, has been confirmed by molecular testing.
  • In this study, 115 <i>M. genitalium</i> DNA-positive samples were analyzed.
  • Fluoroquinolone mutation screening was performed on 86 (74.8%) of the 115 samples, of which 20 (23.3%) samples had a mutation or mutations associated with increased resistance.

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  • [Copyright] Copyright © 2017 American Society for Microbiology.
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  • (PMID = 28878004.001).
  • [ISSN] 1098-660X
  • [Journal-full-title] Journal of clinical microbiology
  • [ISO-abbreviation] J. Clin. Microbiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Mycoplasma genitalium / New Zealand / azithromycin / fluoroquinolone resistance / macrolide resistance / moxifloxacin / treatment failure
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8. Agarwal R, Mohapatra S, Rath GP, Kapil A: Active Surveillance of Health Care Associated Infections in Neurosurgical Patients. J Clin Diagn Res; 2017 Jul;11(7):DC01-DC04

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Active Surveillance of Health Care Associated Infections in Neurosurgical Patients.
  • INTRODUCTION: Health Care Associated Infections (HCAI) are frequent complications in neurosurgery.
  • RESULTS: A total of 330 patients with 4054 patient-days were analysed for HCAI.
  • The overall rate of HCAI was 6.67% and 5.42 per 1000 patient-days.

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  • (PMID = 28892887.001).
  • [ISSN] 2249-782X
  • [Journal-full-title] Journal of clinical and diagnostic research : JCDR
  • [ISO-abbreviation] J Clin Diagn Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Keywords] NOTNLM ; Device associated infection / Infection control / Neurosurgery / Nosocomial infection
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9. Bloom K, Ely A, Arbuthnot P: A T7 Endonuclease I Assay to Detect Talen-Mediated Targeted Mutation of HBV cccDNA. Methods Mol Biol; 2017;1540:85-95

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The technology is being developed for the treatment of viral infections such as persistant hepatitis B virus (HBV).

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  • (PMID = 27975310.001).
  • [ISSN] 1940-6029
  • [Journal-full-title] Methods in molecular biology (Clifton, N.J.)
  • [ISO-abbreviation] Methods Mol. Biol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; HBV / Indels / T7EI / TALEN / cccDNA
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10. Drinkall E, Wass MJ, Coffey TJ, Flynn RJ: A rapid IL-17 response to Cryptosporidium parvum in the bovine intestine. Vet Immunol Immunopathol; 2017 Sep;191:1-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Immunity develops after repeated infections but initial infections can be severe, highlighting the importance of early infection dynamics.
  • IL-17A accumulated over time peaking at 9h post-infection, with no effect of infection on IL-1β; antibiotics positively influenced IL-17A as higher levels were found in cultures with antibiotics.

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  • [Copyright] Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.
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  • (PMID = 28895860.001).
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  • [Journal-full-title] Veterinary immunology and immunopathology
  • [ISO-abbreviation] Vet. Immunol. Immunopathol.
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  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Keywords] NOTNLM ; Biopsy / Bovine / Cryptosporidium parvum / IL-17A / Intestine / Villi
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11. Vimal A, Pal D, Tripathi T, Kumar A: Eucalyptol, sabinene and cinnamaldehyde: potent inhibitors of salmonella target protein L-asparaginase. 3 Biotech; 2017 Aug;7(4):258

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The amino acid residues involved in interactions inside the binding pocket are threonine 115 and threonine 35.
  • The results suggest they could be safe alternatives of chemical compounds to treat infections and combat multidrug-resistant bacteria.

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  • (PMID = 28735432.001).
  • [ISSN] 2190-572X
  • [Journal-full-title] 3 Biotech
  • [ISO-abbreviation] 3 Biotech
  • [Language] eng
  • [Publication-type] Journal Article
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  • [Keywords] NOTNLM ; Antimicrobial / L-Asparaginase / Pathogenicity / S. typhimurium / Spices
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12. Henneberger A, Ertl-Wagner B, Reiser M, Gürkov R, Flatz W: Morphometric evaluation of facial and vestibulocochlear nerves using magnetic resonance imaging: comparison of Menière's disease ears with normal hearing ears. Eur Arch Otorhinolaryngol; 2017 Aug;274(8):3029-3039
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Ann Otol Rhinol Laryngol Suppl 81:26-31, 3; Kariya, Otol Neurotol Off Publ Am Otol Soc Am Neurotol Soc Eur Acad Otol Neurotol 28(8):1063-1068, 4; Megerian Laryngoscope 115(9):1525-1535, 5) but this has yet to be confirmed.
  • The exact pathophysiological mechanisms involved such as viral infections, autoimmune processes, genetic predisposition, cellular apoptosis, and oxidative stress are still not clear.

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  • (PMID = 28584970.001).
  • [ISSN] 1434-4726
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Keywords] NOTNLM ; 3 Tesla / 3D-GE-sequence / CISS / Diameter / Facial nerve / Magnetic resonance imaging / Meniere’s disease / Morphometry / N. VII. / N. VIII / T2w / Vestibulocochlear nerve / cross-sectional area
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13. Cross SN, Potter JA, Aldo P, Kwon JY, Pitruzzello M, Tong M, Guller S, Rothlin CV, Mor G, Abrahams VM: Viral Infection Sensitizes Human Fetal Membranes to Bacterial Lipopolysaccharide by MERTK Inhibition and Inflammasome Activation. J Immunol; 2017 Oct 15;199(8):2885-2895

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Although bacterial infections are commonly identified, other microorganisms may play a role in the pathogenesis.
  • [MeSH-major] Extraembryonic Membranes / immunology. Gammaherpesvirinae / immunology. Herpesviridae Infections / immunology. Herpesvirus 2, Human / immunology. Inflammasomes / metabolism. Premature Birth / immunology. Proto-Oncogene Proteins / metabolism. Receptor Protein-Tyrosine Kinases / metabolism

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  • [Copyright] Copyright © 2017 by The American Association of Immunologists, Inc.
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  • (PMID = 28916522.001).
  • [ISSN] 1550-6606
  • [Journal-full-title] Journal of immunology (Baltimore, Md. : 1950)
  • [ISO-abbreviation] J. Immunol.
  • [Language] eng
  • [Grant] United States / NIAID NIH HHS / AI / R01 AI121183; United States / NIAID NIH HHS / AI / R56 AI124356
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Inflammasomes; 0 / Intercellular Signaling Peptides and Proteins; 0 / Interleukin-1beta; 0 / Lipopolysaccharides; 0 / Proto-Oncogene Proteins; 0 / growth arrest-specific protein 6; EC 2.7.10.1 / MERTK protein, human; EC 2.7.10.1 / Receptor Protein-Tyrosine Kinases
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14. Prabhu VS, Solomkin JS, Medic G, Foo J, Borse RH, Kauf T, Miller B, Sen SS, Basu A: Cost-effectiveness of ceftolozane/tazobactam plus metronidazole versus piperacillin/tazobactam as initial empiric therapy for the treatment of complicated intra-abdominal infections based on pathogen distributions drawn from national surveillance data in the United States. Antimicrob Resist Infect Control; 2017;6:107

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cost-effectiveness of ceftolozane/tazobactam plus metronidazole versus piperacillin/tazobactam as initial empiric therapy for the treatment of complicated intra-abdominal infections based on pathogen distributions drawn from national surveillance data in the United States.
  • BACKGROUND: The prevalence of antimicrobial resistance among gram-negative pathogens in complicated intra-abdominal infections (cIAIs) has increased.
  • RESULTS: Our model results, with baseline resistance levels from the PACTS database, indicated that ceftolozane/tazobactam + metronidazole dominated piperacillin/tazobactam, with lower costs ($44,226/patient vs. $44,811/patient respectively) and higher QALYs (12.85/patient vs. 12.70/patient, respectively).

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  • (PMID = 29090091.001).
  • [ISSN] 2047-2994
  • [Journal-full-title] Antimicrobial resistance and infection control
  • [ISO-abbreviation] Antimicrob Resist Infect Control
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Ceftolozane / Cost-effectiveness analysis / Drug resistance / Intraabdominal infections / Piperacillin / Tazobactam / United States
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15. Dixit A, Tanaka A, Greer JM, Donnelly S: Novel Therapeutics for Multiple Sclerosis Designed by Parasitic Worms. Int J Mol Sci; 2017 Oct 13;18(10)

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  • The evolutionary response to endemic infections with parasitic worms (helminth) was the development of a distinct regulatory immune profile arising from the need to encapsulate the helminths while simultaneously repairing tissue damage.

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  • (PMID = 29027962.001).
  • [ISSN] 1422-0067
  • [Journal-full-title] International journal of molecular sciences
  • [ISO-abbreviation] Int J Mol Sci
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Keywords] NOTNLM ; environmental factors / helminth parasites / immune modulation / innate immunity / multiple sclerosis / old friend’s hypothesis
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16. DeCicco RePass MA, Chen Y, Lin Y, Zhou W, Kaplan DL, Ward HD: Novel Bioengineered Three-Dimensional Human Intestinal Model for Long-Term Infection of Cryptosporidium parvum. Infect Immun; 2017 Mar;85(3)
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We found that <i>C. parvum</i> infected and developed in this tissue model for at least 17 days, the extent of the study time used in the present study.
  • Contents from infected scaffolds could be transferred to fresh scaffolds to establish new infections for at least three rounds.

  • MedlinePlus Health Information. consumer health - Cryptosporidiosis.
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  • [Copyright] Copyright © 2017 American Society for Microbiology.
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  • (PMID = 28052996.001).
  • [ISSN] 1098-5522
  • [Journal-full-title] Infection and immunity
  • [ISO-abbreviation] Infect. Immun.
  • [Language] eng
  • [Grant] United States / NIBIB NIH HHS / EB / P41 EB002520; United States / NIAID NIH HHS / AI / T32 AI007077
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; 3D model / Cryptosporidium / in vitro culture / intestinal epithelial cells
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17. Toth K, Spencer JF, Ying B, Tollefson AE, Wold WSM: HAdV-C6 Is a More Relevant Challenge Virus than HAdV-C5 for Testing Antiviral Drugs with the Immunosuppressed Syrian Hamster Model. Viruses; 2017 Jun 13;9(6)
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Adenovirus infections of immunocompromised patients can cause a severe multi-organ disease that often results in the patients' death.
  • Presently, there are no drugs specifically approved to treat adenovirus infections, and clinicians resort to the off-label use of antivirals that are approved to treat other DNA virus infections, most frequently cidofovir (CDV).
  • CDV, however, has considerable nephrotoxicity, thus it is recommended only for the most severe cases of adenovirus infections.
  • Further, we show for the first time that VGCV, and to a lesser extent CDV, can be used to treat respiratory adenovirus infections in the hamster model.
  • These results extend the utility of the hamster model, and demonstrate the efficacy of two drugs available for clinicians to treat adenovirus infections.

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  • (PMID = 28608847.001).
  • [ISSN] 1999-4915
  • [Journal-full-title] Viruses
  • [ISO-abbreviation] Viruses
  • [Language] eng
  • [Grant] United States / NIAID NIH HHS / AI / HHSN272201000021C; United States / NIAID NIH HHS / AI / HHSN272201000021I
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Keywords] NOTNLM ; adenovirus / animal model / antiviral / hamster
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18. Kumar SN, Mohandas C: An Antifungal Mechanism of Protolichesterinic Acid from the Lichen &lt;i&gt;Usnea albopunctata&lt;/i&gt; Lies in the Accumulation of Intracellular ROS and Mitochondria-Mediated Cell Death Due to Apoptosis in &lt;i&gt;Candida tropicalis&lt;/i&gt;. Front Pharmacol; 2017;8:301

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • <i>Candida</i> species causes superficial and life-threatening systemic infections and are difficult to treat due to the resistance of these organism to various clinically used drugs.
  • Time-kill assay demonstrated that the maximum rate of killing was recorded between 2 and 6 h. <i>C. tropicalis</i> exposed to protolichesterinic acid exhibited an increased ROS production, which is one of the key factors of fungal death.

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  • [ISSN] 1663-9812
  • [Journal-full-title] Frontiers in pharmacology
  • [ISO-abbreviation] Front Pharmacol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Keywords] NOTNLM ; Candida / ROS / apoptosis / mechanism of action / protolichesterinic acid
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19. Roele ED, Timmer VCML, Vaassen LAA, van Kroonenburgh AMJL, Postma AA: Dual-Energy CT in Head and Neck Imaging. Curr Radiol Rep; 2017;5(5):19

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  • Moreover, it can be helpful in imaging of infections and inflammation and parathyroid imaging as supplementary reconstructions can be obtained at lower or equal radiation dose compared with conventional single energy scanning.

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  • (PMID = 28435761.001).
  • [ISSN] 2167-4825
  • [Journal-full-title] Current radiology reports
  • [ISO-abbreviation] Curr Radiol Rep
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Dual-energy CT / Head and neck cancer / Lymph node imaging / Metal artifact reduction / Parathyroid adenoma / Spectral CT
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20. Gifford J, Vaeth E, Richards K, Siddiqui T, Gill C, Wilson L, DeLisle S: Decision support during electronic prescription to stem antibiotic overuse for acute respiratory infections: a long-term, quasi-experimental study. BMC Infect Dis; 2017 Jul 31;17(1):528

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Decision support during electronic prescription to stem antibiotic overuse for acute respiratory infections: a long-term, quasi-experimental study.
  • BACKGROUND: Interventions to support decision-making can reduce inappropriate antibiotic use for acute respiratory infections (ARI), but they may not be sustainable.
  • The objective of the study is to evaluate the long-term effectiveness of a clinical decision-support system (CDSS) interposed at the time of electronic (e-) prescriptions for selected antibiotics.
  • For fluoroquinolones, guideline concordance decreased from 88.6% (39 of 44 visits) to 51.3% (59 of 115 visits), pre- vs. post-withdrawal periods (p < 0.005).
  • Concordance did not change between those same time periods for antibiotics that were never subjected to the intervention ("All Other Antibiotics").
  • CONCLUSIONS: A CDSS interposed at the time of e-prescription of selected antibiotics can shift their use toward ARI treatment guidelines, and this effect can be maintained over the long term as long as the CDSS remains in place.
  • [MeSH-major] Anti-Bacterial Agents / therapeutic use. Decision Support Systems, Clinical. Electronic Prescribing / statistics & numerical data. Prescription Drug Overuse / prevention & control. Respiratory Tract Infections / drug therapy

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  • (PMID = 28760143.001).
  • [ISSN] 1471-2334
  • [Journal-full-title] BMC infectious diseases
  • [ISO-abbreviation] BMC Infect. Dis.
  • [Language] eng
  • [Publication-type] Journal Article; Observational Study
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 0 / Fluoroquinolones; 83905-01-5 / Azithromycin; L4618BD7KJ / gatifloxacin
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21. Cheng K, Van de Waal DB, Niu XY, Zhao YJ: Combined Effects of Elevated &lt;i&gt;p&lt;/i&gt;CO&lt;sub&gt;2&lt;/sub&gt; and Warming Facilitate Cyanophage Infections. Front Microbiol; 2017;8:1096

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Combined Effects of Elevated <i>p</i>CO<sub>2</sub> and Warming Facilitate Cyanophage Infections.
  • At several time points during the 1 year period, and upon re-exposure, we measured various infection characteristics of it associated cyanophage PP, including the burst size, latent period, lytic cycle and the efficiency of plaquing (EOP).
  • Our results demonstrate that adaptation but particularly physiological acclimation to climate change conditions favored viral infections, while limited host plasticity and slow adaptation after re-exposure to control conditions impeded host biomass build-up and viral infections.

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  • (PMID = 28659906.001).
  • [ISSN] 1664-302X
  • [Journal-full-title] Frontiers in microbiology
  • [ISO-abbreviation] Front Microbiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Keywords] NOTNLM ; EOP / climate change / common garden experiment / cyanobacterial virus / infectivity / one-step growth curve
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22. Slaats J, Ten Oever J, van de Veerdonk FL, Netea MG: IL-1β/IL-6/CRP and IL-18/ferritin: Distinct Inflammatory Programs in Infections. PLoS Pathog; 2016 Dec;12(12):e1005973
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] IL-1β/IL-6/CRP and IL-18/ferritin: Distinct Inflammatory Programs in Infections.
  • The host inflammatory response against infections is characterized by the release of pro-inflammatory cytokines and acute-phase proteins, driving both innate and adaptive arms of the immune response.
  • This review discusses the profiles of acute-phase proteins and circulating cytokines encountered in viral and bacterial infections.
  • We also propose a model in which the inflammatory response to viral (IL-18/ferritin) and bacterial (IL-6/CRP) infections presents with specific plasma patterns of immune biomarkers.
  • [MeSH-major] Acute-Phase Proteins / immunology. Bacterial Infections / immunology. Cytokines / immunology. Inflammation / immunology. Virus Diseases / immunology

  • MedlinePlus Health Information. consumer health - Bacterial Infections.
  • MedlinePlus Health Information. consumer health - Viral Infections.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
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  • (PMID = 27977798.001).
  • [ISSN] 1553-7374
  • [Journal-full-title] PLoS pathogens
  • [ISO-abbreviation] PLoS Pathog.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Acute-Phase Proteins; 0 / Cytokines; 0 / Inflammation Mediators; 0 / Interleukin-18; 0 / Interleukin-1beta; 0 / Interleukin-6; 9007-41-4 / C-Reactive Protein; 9007-73-2 / Ferritins
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23. Fonseca LL, Joyner CJ, MaHPIC Consortium, Galinski MR, Voit EO: A model of Plasmodium vivax concealment based on Plasmodium cynomolgi infections in Macaca mulatta. Malar J; 2017 Sep 18;16(1):375

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A model of Plasmodium vivax concealment based on Plasmodium cynomolgi infections in Macaca mulatta.
  • The total parasite biomass during infections is correlated with the severity of disease but not necessarily quantified accurately by microscopy.
  • METHODS: Time series data tracking the longitudinal development of parasitaemia in five Macaca mulatta infected with P. cynomolgi were used to design a computational model quantifying iRBCs that circulate in the blood versus those that are not detectable and are termed here as 'concealed'.
  • This inference has implications for understanding vivax biology and pathogenesis and stresses the importance of considering a concealed parasite reservoir with regard to vivax epidemiology and the quantification and treatment of P. vivax infections.

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  • (PMID = 28923058.001).
  • [ISSN] 1475-2875
  • [Journal-full-title] Malaria journal
  • [ISO-abbreviation] Malar. J.
  • [Language] eng
  • [Grant] United States / NIAID NIH HHS / AI / HHSN272201200031C; United States / NIH HHS / OD / P51 OD011132
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Host–pathogen interactions / Malaria / Mathematical model / Parasite dynamics / Plasmodium falciparum / Sequestration / Systems biology
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24. Kim GS, Lee KS, Park CK, Kang SK, Kim DW, Oh SG, Oh BS, Jung Y, Kim S, Yun JS, Song SY, Na KJ, Jeong IS, Ahn BH: Nosocomial Infection in Adult Patients Undergoing Veno-Arterial Extracorporeal Membrane Oxygenation. J Korean Med Sci; 2017 Apr;32(4):593-598

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Data on the frequency of nosocomial infections during extracorporeal membrane oxygenation (ECMO) in adult populations remain scarce.
  • We investigated the risk factors for nosocomial infections in adult patients undergoing venoarterial ECMO (VA-ECMO) support.
  • Mean patient age was 60.6 ± 14.3 years and 21 (34.4%) patients were female.
  • There were 18 nosocomial infections in 14 (23.0%) patients.
  • These included respiratory tract infections in 9 cases and bloodstream infections in a further 9.
  • Therefore, to avoid the development of nosocomial infections, strategies to shorten the length of ECMO support should be applied whenever possible.
  • [MeSH-minor] Adult. Aged. Creatinine / blood. Female. Gram-Negative Bacteria / isolation & purification. Humans. Incidence. Male. Middle Aged. Multivariate Analysis. Odds Ratio. Proportional Hazards Models. Respiratory Tract Infections / diagnosis. Respiratory Tract Infections / therapy. Risk Factors. Shock, Cardiogenic / etiology. Time Factors. Young Adult

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  • [Copyright] © 2017 The Korean Academy of Medical Sciences.
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  • [Publication-type] Journal Article
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  • [Keywords] NOTNLM ; Extracorporeal Membrane Oxygenation Support / Infection
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25. Park J, Ramanathan R, Pham L, Woodrow KA: Chitosan enhances nanoparticle delivery from the reproductive tract to target draining lymphoid organs. Nanomedicine; 2017 Aug;13(6):2015-2025
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • These observations indicate that chitosan may have great potential as an adjuvant for both local and systemic protective immunity against viral infections in the FRT.

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  • [Copyright] Copyright © 2017 Elsevier Inc. All rights reserved.
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  • (PMID = 28435136.001).
  • [ISSN] 1549-9642
  • [Journal-full-title] Nanomedicine : nanotechnology, biology, and medicine
  • [ISO-abbreviation] Nanomedicine
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / DP2 HD075703; United States / NIAID NIH HHS / AI / R21 AI094412; United States / NIAID NIH HHS / AI / R33 AI094412; United States / NIAID NIH HHS / AI / R56 AI074661
  • [Publication-type] Journal Article
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  • [Keywords] NOTNLM ; Chitosan / Draining lymph node / Mucosal delivery / Nanoparticle / Reproductive tract
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26. Montespan C, Wiethoff CM, Wodrich H: A Small Viral PPxY Peptide Motif To Control Antiviral Autophagy. J Virol; 2017 Sep 15;91(18)

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This mechanism, also termed selective autophagy, is well characterized for invasive bacteria but remains poorly documented for viral infections.

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  • [Copyright] Copyright © 2017 American Society for Microbiology.
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  • (PMID = 28659475.001).
  • [ISSN] 1098-5514
  • [Journal-full-title] Journal of virology
  • [ISO-abbreviation] J. Virol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Peptides
  • [Keywords] NOTNLM ; adenoviruses / autophagy / innate immunity / virus entry
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27. Halaji M, Hashempour T, Pouladfar GR, Ghasabi F, Khashei R: Atypical bacterial etiology of acute respiratory infections and clinical characterizations among Iranian children. Cell Mol Biol (Noisy-le-grand); 2017 Aug 30;63(8):115-119

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical bacterial etiology of acute respiratory infections and clinical characterizations among Iranian children.
  • Acute respiratory infections (ARIs) in children younger than 5 years of age are one of the leading causes of morbidity and mortality, particularly in developing countries.

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  • (PMID = 28886324.001).
  • [ISSN] 1165-158X
  • [Journal-full-title] Cellular and molecular biology (Noisy-le-Grand, France)
  • [ISO-abbreviation] Cell. Mol. Biol. (Noisy-le-grand)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
  • [Keywords] NOTNLM ; ARIs / Chlamydophila pneumoniae / Mycoplasma pneumoniae / PCR.
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28. Panariello BHD, Klein MI, Pavarina AC, Duarte S: Inactivation of genes TEC1 and EFG1 in &lt;i&gt;Candida albicans&lt;/i&gt; influences extracellular matrix composition and biofilm morphology. J Oral Microbiol; 2017;9(1):1385372

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • <b>Background</b>: Infections caused by <i>Candida</i> spp. have been associated with formation of a biofilm, i.e. a complex microstructure of cells adhering to a surface and embedded within an extracellular matrix (ECM).

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  • (PMID = 29081917.001).
  • [ISSN] 2000-2297
  • [Journal-full-title] Journal of oral microbiology
  • [ISO-abbreviation] J Oral Microbiol
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29. Agrawal A: Dendritic Cell-Airway Epithelial Cell Cross-Talk Changes with Age and Contributes to Chronic Lung Inflammatory Diseases in the Elderly. Int J Mol Sci; 2017 Jun 06;18(6)

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The interaction between DCs and AECs plays a crucial role in lung immunity at homeostasis and during infections.

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  • (PMID = 28587289.001).
  • [ISSN] 1422-0067
  • [Journal-full-title] International journal of molecular sciences
  • [ISO-abbreviation] Int J Mol Sci
  • [Language] eng
  • [Grant] United States / NIA NIH HHS / AG / R01 AG045216; United States / NCATS NIH HHS / TR / UL1 TR000153
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Keywords] NOTNLM ; age / airway epithelial cells / crosstalk / dendritic cells / human / inflammation
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30. Sudharsanan S, Gs S, Sureshkumar S, Vijayakumar C, Sujatha S, Kate V: Does Fine Needle Aspiration Microbiology Offer Any Benefit Over Wound Swab in Detecting the Causative Organisms in Surgical Site Infections? Wounds; 2017 Sep;29(9):255-261

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Does Fine Needle Aspiration Microbiology Offer Any Benefit Over Wound Swab in Detecting the Causative Organisms in Surgical Site Infections?
  • OBJECTIVE: The objective of this study is to determine the role of ne needle aspiration microbiology (FNAM) in detecting the causative organisms of postoperative surgical site infections (SSIs) in comparison with the standard technique of surface swabbing.
  • RESULTS: A total of 115 positive cultures were obtained from the 150 patients with SSIs; surface swab was positive in 110 cases and FNAM was positive in 94 cases.
  • In certain cases with unexplained wound infections, FNAM can be used as an investigation to identify speci c pathogens not detected by conventional surface swab.

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  • (PMID = 28678732.001).
  • [ISSN] 1943-2704
  • [Journal-full-title] Wounds : a compendium of clinical research and practice
  • [ISO-abbreviation] Wounds
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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31. Amaral AJ, Andrade J, Foxall RB, Matoso P, Matos AM, Soares RS, Rocha C, Ramos CG, Tendeiro R, Serra-Caetano A, Guerra-Assunção JA, Santa-Marta M, Gonçalves J, Gama-Carvalho M, Sousa AE: miRNA profiling of human naive CD4 T cells links miR-34c-5p to cell activation and HIV replication. EMBO J; 2017 Feb 01;36(3):346-360
Genetic Alliance. consumer health - HIV.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Our results demonstrate, for the first time, the transcriptional up-regulation of miR-34c-5p in response to TCR stimulation in naive CD4 T cells.
  • The induction of this miR was further consistently found to be reduced by both HIV-1 and HIV-2 infections.

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  • [Copyright] © 2016 The Authors.
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  • (PMID = 27993935.001).
  • [ISSN] 1460-2075
  • [Journal-full-title] The EMBO journal
  • [ISO-abbreviation] EMBO J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / MIRN34 microRNA, human; 0 / MicroRNAs; 0 / Receptors, Antigen, T-Cell
  • [Keywords] NOTNLM ; HIV‐1 / HIV‐2 / T‐cell activation / miR‐34c‐5p / naive CD4 T cells
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32. Wijesekara PNK, Kumbukgolla WW, Jayaweera JAAS, Rawat D: Review on Usage of Vancomycin in Livestock and Humans: Maintaining Its Efficacy, Prevention of Resistance and Alternative Therapy. Vet Sci; 2017 Jan 26;4(1)

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Vancomycin is one of the "last-line" classes of antibiotics used in the treatment of life-threatening infections caused by Gram-positive bacteria.
  • Even though vancomycin was discovered in the 1950s, it was widely used after the 1980s for the treatment of infections caused by methicillin-resistant <i>Staphylococci</i>, as the prevalence of these strains were increased.

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  • (PMID = 29056665.001).
  • [ISSN] 2306-7381
  • [Journal-full-title] Veterinary sciences
  • [ISO-abbreviation] Vet Sci
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Keywords] NOTNLM ; alternatives / broad view / rational use / vancomycin / veterinary use at a glance
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33. Marvin SA: The Immune Response to Astrovirus Infection. Viruses; 2016 Dec 30;9(1)

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Studies from humans and animals suggest that adaptive immunity is important in restricting classic and novel astrovirus infections, while studies from animal models and cell culture systems suggest that an innate immune system plays a role in limiting astrovirus replication.
  • [MeSH-major] Astroviridae / immunology. Astroviridae Infections / immunology

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  • (PMID = 28042824.001).
  • [ISSN] 1999-4915
  • [Journal-full-title] Viruses
  • [ISO-abbreviation] Viruses
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Keywords] NOTNLM ; adaptive immunity / astrovirus infection / astrovirus replication / immune response / innate immunity / type I interferon
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34. Noor MT, Manoria P: Immune Dysfunction in Cirrhosis. J Clin Transl Hepatol; 2017 Mar 28;5(1):50-58

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This increased bacterial translocation and consequent endotoxemia leads to increased blood stream bacterial infections that cause systemic inflammatory response syndrome, sepsis, multiorgan failure and death.
  • Prompt diagnosis and treatment of such infections are necessary for better survival.

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  • (PMID = 28507927.001).
  • [ISSN] 2225-0719
  • [Journal-full-title] Journal of clinical and translational hepatology
  • [ISO-abbreviation] J Clin Transl Hepatol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] China
  • [Keywords] NOTNLM ; Cirrhosis / Immune dysfunction / Inflammation / Liver disease
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35. Bilgic HB, Bakırcı S, Kose O, Unlu AH, Hacılarlıoglu S, Eren H, Weir W, Karagenc T: Prevalence of tick-borne haemoparasites in small ruminants in Turkey and diagnostic sensitivity of single-PCR and RLB. Parasit Vectors; 2017 Apr 27;10(1):211

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The diagnostic sensitivity of these two approaches was then compared in terms of their ability to detect single species and mixed infections.
  • OT1, T. luwenshuni and T. uilenbergi in Turkey was revealed for the first time while the presence of Babesia motasi, B. crassa and T. separata in Turkish small ruminants was confirmed using molecular methods.
  • More than 80% of the mixed infections contained T. ovis and/or A. ovis.
  • The RLB approach was found to be capable of detecting mixed infections with species such as Theileria sp.
  • However, the latter approach was still capable of identifying a high proportion of individuals containing mixed-species infections.

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  • (PMID = 28449722.001).
  • [ISSN] 1756-3305
  • [Journal-full-title] Parasites & vectors
  • [ISO-abbreviation] Parasit Vectors
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Goat / Prevalence / RLB / Sheep / Species-specific PCR / Tick-borne pathogens / Turkey
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36. Minutti CM, Drube S, Blair N, Schwartz C, McCrae JC, McKenzie AN, Kamradt T, Mokry M, Coffer PJ, Sibilia M, Sijts AJ, Fallon PG, Maizels RM, Zaiss DM: Epidermal Growth Factor Receptor Expression Licenses Type-2 Helper T Cells to Function in a T Cell Receptor-Independent Fashion. Immunity; 2017 Oct 17;47(4):710-722.e6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Gastro-intestinal helminth infections trigger the release of interleukin-33 (IL-33), which induces type-2 helper T cells (Th2 cells) at the site of infection to produce IL-13, thereby contributing to host resistance in a T cell receptor (TCR)-independent manner.
  • [MeSH-minor] Amphiregulin / immunology. Amphiregulin / metabolism. Animals. Cell Line. Cells, Cultured. Gene Expression / genetics. Gene Expression / immunology. Gene Expression Profiling / methods. HEK293 Cells. Humans. MAP Kinase Signaling System / immunology. Mice, Inbred C57BL. Mice, Knockout. Mice, Transgenic. Nematospiroides dubius / immunology. Nematospiroides dubius / physiology. Nocardia / immunology. Nocardia / physiology. Nocardia Infections / immunology. Nocardia Infections / metabolism. Nocardia Infections / microbiology. Reverse Transcriptase Polymerase Chain Reaction. Strongylida Infections / immunology. Strongylida Infections / metabolism. Strongylida Infections / parasitology

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  • [Copyright] Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.
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  • (PMID = 29045902.001).
  • [ISSN] 1097-4180
  • [Journal-full-title] Immunity
  • [ISO-abbreviation] Immunity
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Amphiregulin; 0 / Interleukin-13; 0 / Interleukin-33; 0 / Receptors, Antigen, T-Cell; EC 2.7.10.1 / Receptor, Epidermal Growth Factor
  • [Keywords] NOTNLM ; TCR-independent IL-13 secretion / cytokine signaling / gastro-intestinal helminth infections / interleukin-13 / interleukin-33 / type-2 helper T cells
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37. Maier M, Takano T, Sapir-Pichhadze R: Changing Paradigms in the Management of Rejection in Kidney Transplantation: Evolving From Protocol-Based Care to the Era of P4 Medicine. Can J Kidney Health Dis; 2017;4:2054358116688227

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Pharmacogenomics are discussed as means to facilitate personalized immunosuppression regimens and promotion of active patient participation as a means to improve adherence.
  • P4 medicine, however, should more broadly address health concerns in kidney transplant recipients, including competing outcomes such as infections, malignancies, and cardiovascular disease.

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  • (PMID = 28270929.001).
  • [Journal-full-title] Canadian journal of kidney health and disease
  • [ISO-abbreviation] Can J Kidney Health Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; adherence / biomarkers / immune competency / pharmacogenomics / surveillance
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38. Kittayapong P, Olanratmanee P, Maskhao P, Byass P, Logan J, Tozan Y, Louis V, Gubler DJ, Wilder-Smith A: Mitigating Diseases Transmitted by Aedes Mosquitoes: A Cluster-Randomised Trial of Permethrin-Impregnated School Uniforms. PLoS Negl Trop Dis; 2017 Jan;11(1):e0005197
Hazardous Substances Data Bank. PERMETHRIN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The primary endpoint was laboratory-confirmed dengue infections.
  • In the control schools, 24/641 (3.7%) and in the intervention schools 33/1,014 (3.3%) students had evidence of new dengue infections during one school term (5 months).
  • There was no significant difference in proportions of students having incident dengue infections between the intervention and control schools, with adjustment for clustering by school.
  • However, there was no serological evidence of protection against dengue infections over the five months school term, best explained by the rapid washing-out of permethrin after 4 washes.

  • MedlinePlus Health Information. consumer health - Chikungunya.
  • MedlinePlus Health Information. consumer health - Dengue.
  • MedlinePlus Health Information. consumer health - Zika Virus.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
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  • [ISSN] 1935-2735
  • [Journal-full-title] PLoS neglected tropical diseases
  • [ISO-abbreviation] PLoS Negl Trop Dis
  • [Language] eng
  • [Databank-accession-numbers] ClinicalTrials.gov/ NCT01563640
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39. González-Alcaide G, Peris J, Ramos JM: Areas of research and clinical approaches to the study of liver abscess. World J Gastroenterol; 2017 Jan 14;23(2):357-365
MedlinePlus Health Information. consumer health - Liver Cancer.

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  • The most active areas of research in the field are diagnosis <i>via</i> computerized tomography scan, differential diagnosis with regard to liver cancer, treatment with antimicrobial agents, and <i>Klebsiella</i> infections (including bacteremia).
  • [MeSH-minor] Anti-Infective Agents / therapeutic use. China. Diagnosis, Differential. Entamoeba histolytica. Humans. Incidence. India. Japan. Klebsiella Infections / complications. Liver Abscess, Amebic / parasitology. Liver Abscess, Pyogenic / microbiology. Mexico. Republic of Korea. Research Personnel. Taiwan. Tomography, X-Ray Computed. United States

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  • (PMID = 28127209.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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  • [Keywords] NOTNLM ; Amebic abscess / Bibliometrics / Cluster analysis / Liver abscess / Pyogenic abscess
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40. Evangelisti E, Gogleva A, Hainaux T, Doumane M, Tulin F, Quan C, Yunusov T, Floch K, Schornack S: Time-resolved dual transcriptomics reveal early induced Nicotiana benthamiana root genes and conserved infection-promoting Phytophthora palmivora effectors. BMC Biol; 2017 May 11;15(1):39

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Time-resolved dual transcriptomics reveal early induced Nicotiana benthamiana root genes and conserved infection-promoting Phytophthora palmivora effectors.
  • RESULTS: We employed the model plant Nicotiana benthamiana to study the P. palmivora root infections at the cellular and molecular levels.
  • Time-resolved dual transcriptomics revealed different pathogen and host transcriptome dynamics.
  • CONCLUSIONS: These results constitute a major advance in our understanding of P. palmivora diseases and establish extensive resources for P. palmivora pathogenomics, effector-aided resistance breeding and the generation of induced resistance to Phytophthora root infections.

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